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Chemical Senses, 41 (1), 6976
A prospective randomized trial of diltiazem and glyceryltrinitrate ointment in the treatment of chronic anal fissure
Although species differences and dosing regimens vary, the overall direction of the biochemical effect remains consistent across models
Initial Treatment Phase Most patients require: 6 to 10 sessions 1 to 2 sessions weekly Maintenance Phase After achieving desired results: Maintenance injections every 48 weeks Duration of Effects Results may last several months depending on: Sun exposure Lifestyle habits Skincare routine Smoking status Diet and hydration Proper sun protection significantly extends visible results
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